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  • 2-十八烯酸单甘油酯

    2-oleoylglycerol

化合物简介

2-Oleoylglycerol (2OG) is a monoacylglycerol that is found in biologic tissues. Its synthesis is derived from diacylglycerol precursors. It is metabolized to oleic acid and glycerol primarily by the enzyme monoacylglycerol lipase (MAGL). In 2011, 2OG was found to be an endogenous ligand to GPR119. 2OG has been shown to increase glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) levels following administration to the small intestine.

基本信息

CAS:3443-84-3
中文别名:2-甘油单油酸酯;
英文别名:glycerine monooleate;2-o-Kresyloxy-glutarsaeure-diethylester;2-MONOOLEIN;1,3-dihydroxypropan-2-yl oleate;2-monooleoylglycerol;glycerin oleate;2-Oleoylglycerol;
分子式:C21H40O4
分子量:356.54
精确质量:356.293
Psa:66.76
Logp:4.9203

编号系统

物化性质

密度:0.969 g/cm3
沸点:485.4ºC at 760mmHg
闪点:113ºC
折射率:1.478
储存条件:-20ºC

安全信息

WGK Germany:3

生产方法及用途

合成路线

上游原料

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图谱

13C NMR : Predict


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