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化合物简介
2-Oleoylglycerol (2OG) is a monoacylglycerol that is found in biologic tissues. Its synthesis is derived from diacylglycerol precursors. It is metabolized to oleic acid and glycerol primarily by the enzyme monoacylglycerol lipase (MAGL). In 2011, 2OG was found to be an endogenous ligand to GPR119. 2OG has been shown to increase glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) levels following administration to the small intestine.
基本信息
CAS:3443-84-3
中文别名:2-甘油单油酸酯;
英文别名:glycerine monooleate;2-o-Kresyloxy-glutarsaeure-diethylester;2-MONOOLEIN;1,3-dihydroxypropan-2-yl oleate;2-monooleoylglycerol;glycerin oleate;2-Oleoylglycerol;
分子式:C21H40O4
分子量:356.54
精确质量:356.293
Psa:66.76
Logp:4.9203
中文别名:2-甘油单油酸酯;
英文别名:glycerine monooleate;2-o-Kresyloxy-glutarsaeure-diethylester;2-MONOOLEIN;1,3-dihydroxypropan-2-yl oleate;2-monooleoylglycerol;glycerin oleate;2-Oleoylglycerol;
分子式:C21H40O4
分子量:356.54
精确质量:356.293
Psa:66.76
Logp:4.9203
编号系统
物化性质
密度:0.969 g/cm3
沸点:485.4ºC at 760mmHg
闪点:113ºC
折射率:1.478
储存条件:-20ºC
沸点:485.4ºC at 760mmHg
闪点:113ºC
折射率:1.478
储存条件:-20ºC
安全信息
WGK Germany:3
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict











