Norethisterone (INN, BAN), also known as norethindrone (USAN), as well as 19-nor-17α-ethynyltestosterone, but more commonly known under its trade name Utovlan®, is a steroidal progestin used in some combined oral contraceptive pills and progestogen-only pills, and also available as a standalone drug. It can be used to treat premenstrual syndrome, painful periods, abnormal heavy bleeding, irregular periods, menopausal syndrome (in combination with estrogen), or to postpone a period. It is also commonly used to help prevent uterine hemorrhage in complicated non-surgical or pre-surgical gynecologic cases and in treating non responsive cyclical mastalgia. Norethisterone was the first orally highly active progestin to be synthesized.

CAS：68-22-4
中文别名：17α-乙炔基-17β-羟基-19-去甲-4-雄甾烯-3-酮;17α-乙炔基-19-去甲睾酮;17α-Ethynyl-19-nortestosterone;4-19-去甲基雄烯二醇;去甲基脱氢羟孕酮;19诺塞睾甾酮;17-羟基-19-去甲-17α-孕甾-4-烯-20-炔基-3-酮;19-去甲-17α-乙炔基-4-雄甾烯-17β-醇-3-酮;氯塞酮;
英文别名：Mini-Pe;Norethindrone;Noriday;triella;sc4640;Anovule;Norfor;Gestest;ENT;NET;19-Norpregn-4-en-20-yn-3-one, 17-hydroxy-, (17 -)-;
分子式：C20H26O2
分子量：298.419
精确质量：298.193
Psa：37.3
Logp：3.4925

UNII：T18F433X4S

外观与性状：灰白色至淡黄色固体
密度：1.15 g/cm3
沸点：447ºC at 760 mmHg
熔点：205-206°C(lit.)
折射率：1.577
储存条件：-20ºC Freezer

RTECS号：RC8975000
安全说明：S22; S36/37/39; S45; S26
WGK Germany：3
危险类别码：R40
海关编码：2937290090
危险品标志：Xn
危险标志：GHS08
信号词：Warning
危险性描述：H351

生产方法
1.可由醋酸妊娠烯醇酮合成 孕激素类药,用于月经不调、子宫功能性出血、子宫内膜异位症等
用途
孕激素类药,用于月经不调、子宫功能性出血、子宫内膜异位症等