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化合物简介

Lynestrenol (INN, USAN, BAN, JAN), also known as 17α-ethinyl-3-desoxy-19-nortestosterone or 17α-ethynyl-4-estren-17β-ol, is a steroidal progestin. It is a synthetic, orally active progestogen associated with numerous effects of the natural progesterone hormone. Lynestrenol has a strong progestational effect on the uterine endometrium (transforming proliferative endometrium into secretory one), inhibits secretion of gonadotropin, suppresses maturation of follicles in the ovaries and ovulation, reduces menstrual bleeding. This synthetic gestagen is associated with minimal estrogenic, androgenic and anabolic effects. Lynestrenol is used in treatment of hormonal disorders and diseases caused by insufficient secretion of the natural progesterone, except in case of risky pregnancies and prevention of miscarriage, since it is not efficient enough in this indication.

基本信息

CAS:52-76-6
中文别名:类兴盖斯托;
英文别名:org485-50;exluten;ethinylestrenol;19-Nor-4-pregnen-20-yn-17β-ol;exluton;lynenol;orgametil;LYNDIOL;Exlutena;exlutona;lynoestrenol;exlution;
分子式:C20H28O
分子量:284.436
精确质量:284.214
Psa:20.23
Logp:4.3135

编号系统

UNII:N2Z8ALG4U5

物化性质

密度:1.08 g/cm3
沸点:399.6ºC at 760 mmHg
熔点:158ºC
闪点:176.9ºC
折射率:1.567

安全信息

生产方法及用途

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图谱

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