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化合物简介
Bolandione, also known as 19-norandrostenedione (19-norandrost-4-en-3,17-dione), is a precursor of the anabolic steroid nandrolone. Until 2005, bolandione was available without prescription in United States, where it was marketed as a prohormone, but it is now classified as a Schedule III drug. It is also banned from use in many sports, including the Olympic Games, under the World Anti-Doping Code. Bolandione is readily metabolized to nandrolone after oral administration, but its potency to transactivate the androgen receptor dependent reporter gene expression is 10 times lower as compared to dihydrotestosterone (DHT).
基本信息
CAS:734-32-7
中文别名:甲基固烯双酮;雌二醇杂质;19-去甲雄烯二酮;雌甾-4-烯-3,17-二酮;19-去甲-4-雄烯二酮;19-去甲雄甾-4-烯-3,17-二酮;
英文别名:19-nor-4-androstenedione;dl-19-norandrost-4-ene-3,17-dione;19-NORANDROSTENDIONE;4-ESTRENE-3,17-DIONE;Estr-4-ene-3,17-dione;19-nor-4-androstene-3;19-nor-androst-4-ene-3,17-dione;19-NORANDROSTENEDIONE;19-nor-4-androstene-3,17-dione;Nor-4-Androstenedione;19-Norandrost-4-ene-3,17-dione;4-ESTREN-3,17-DIONE;
分子式:C18H24O2
分子量:272.382
精确质量:272.178
Psa:34.14
Logp:3.6973
中文别名:甲基固烯双酮;雌二醇杂质;19-去甲雄烯二酮;雌甾-4-烯-3,17-二酮;19-去甲-4-雄烯二酮;19-去甲雄甾-4-烯-3,17-二酮;
英文别名:19-nor-4-androstenedione;dl-19-norandrost-4-ene-3,17-dione;19-NORANDROSTENDIONE;4-ESTRENE-3,17-DIONE;Estr-4-ene-3,17-dione;19-nor-4-androstene-3;19-nor-androst-4-ene-3,17-dione;19-NORANDROSTENEDIONE;19-nor-4-androstene-3,17-dione;Nor-4-Androstenedione;19-Norandrost-4-ene-3,17-dione;4-ESTREN-3,17-DIONE;
分子式:C18H24O2
分子量:272.382
精确质量:272.178
Psa:34.14
Logp:3.6973
编号系统
UNII:U90987PVU5
物化性质
密度:1.106g/mLat 25°C(lit.)
沸点:63-66°C10mm Hg(lit.)
熔点:−72°C(lit.)
闪点:80°F
折射率:n20/D 1.457(lit.)
水溶解性:insoluble
储存条件:Refrigerator
沸点:63-66°C10mm Hg(lit.)
熔点:−72°C(lit.)
闪点:80°F
折射率:n20/D 1.457(lit.)
水溶解性:insoluble
储存条件:Refrigerator
安全信息
安全说明:S16; S26; S36/37/39; S45
WGK Germany:3
危险类别码:R11
危险品标志:F; C
WGK Germany:3
危险类别码:R11
危险品标志:F; C
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict

1H NMR : Predict
