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化合物简介
Hordenine (N,N-dimethyltyramine) is an alkaloid of the phenethylamine class that occurs naturally in a variety of plants, taking its name from one of the most common, barley (Hordeum species). Chemically, hordenine is the N-methyl derivative of N-methyltyramine, and the N,N-dimethyl derivative of the well-known biogenic amine tyramine, from which it is biosynthetically derived and with which it shares some pharmacological properties (see below). Currently, hordenine is widely sold as an ingredient of nutritional supplements, with the claims that it is a stimulant of the central nervous system, and has the ability to promote weight loss by enhancing metabolism. In experimental animals, given sufficiently large doses parenterally (i.e. by injection), hordenine does produce an increase in blood pressure, as well as other disturbances of the cardio-vascular, respiratory and nervous systems. These effects are generally not reproduced by oral administration of the drug in test animals, and there are virtually no scientific reports of the effects of hordenine in human beings. More detailed discussions of hordenine pharmacology and toxicology are given below this section.
基本信息
CAS:539-15-1
中文别名:4-羟基-N,N-二甲基苯乙胺;4-(2-二甲基氨基乙基)苯酚;麦芽碱;大麦碱;安哈林;對羥-N,N-二甲苯乙胺;氮位N,N-二甲基对羟基苯乙胺;4-[2-(二甲基氨基)乙基]苯酚;
英文别名:4-[2-(Dimethylamino)ethyl]phenol;Cactine;Anhaline;N,N-dimethyltyramine;Hordenin;Phenol, 4-[2-(dimethylamino)ethyl]-;Hordetin;p-[2-(dimethylamino)ethyl]phenol;Hordenine;4-(2-(Dimethylamino)ethyl)phenol;Ordenina;Eremursine;2-(4-Hydroxyphenyl)-N,N-dimethylethylamine (4-(2-Dimethylaminoethyl)phenol;Anhalin;4-Hydroxy-N,N-dimethylphenethylamine;4-[2-(dimethylamino)ethyl]phenol;Anhalin-d6;N,N-dimethyl-2-(4-hydroxyphenyl)ethylamine;Ordenine;
分子式:C10H15NO
分子量:165.232
精确质量:165.115
Psa:23.47
Logp:1.4963
中文别名:4-羟基-N,N-二甲基苯乙胺;4-(2-二甲基氨基乙基)苯酚;麦芽碱;大麦碱;安哈林;對羥-N,N-二甲苯乙胺;氮位N,N-二甲基对羟基苯乙胺;4-[2-(二甲基氨基)乙基]苯酚;
英文别名:4-[2-(Dimethylamino)ethyl]phenol;Cactine;Anhaline;N,N-dimethyltyramine;Hordenin;Phenol, 4-[2-(dimethylamino)ethyl]-;Hordetin;p-[2-(dimethylamino)ethyl]phenol;Hordenine;4-(2-(Dimethylamino)ethyl)phenol;Ordenina;Eremursine;2-(4-Hydroxyphenyl)-N,N-dimethylethylamine (4-(2-Dimethylaminoethyl)phenol;Anhalin;4-Hydroxy-N,N-dimethylphenethylamine;4-[2-(dimethylamino)ethyl]phenol;Anhalin-d6;N,N-dimethyl-2-(4-hydroxyphenyl)ethylamine;Ordenine;
分子式:C10H15NO
分子量:165.232
精确质量:165.115
Psa:23.47
Logp:1.4963
编号系统
EINECS号:208-710-4
物化性质
密度:1.026g/cm3
沸点:270.2ºC at 760 mmHg
闪点:123.5ºC
折射率:1.542
沸点:270.2ºC at 760 mmHg
闪点:123.5ºC
折射率:1.542
安全信息
海关编码:2922199090
生产方法及用途
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图谱
13C NMR : Predict

1H NMR : Predict

Mass spectrum (electron ionization)
