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  • O-去甲文拉法辛

    O-desmethylvenlafaxine

化合物简介

Desvenlafaxine (brand name: Pristiq, Desfax), also known as O-desmethylvenlafaxine, is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class developed and marketed by Wyeth (now part of Pfizer). Desvenlafaxine is a synthetic form of the major active metabolite of venlafaxine (sold under the brand names Effexor and Efexor). It is being targeted as the first non-hormonal based treatment for menopause.

基本信息

CAS:93413-62-8
中文别名:1-[2-(二甲胺基)-1-(4-羟基苯基)乙基]环己醇;米那普伦盐酸盐;去甲文拉法辛;
英文别名:4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol;4-(2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)phenol;
分子式:C16H25NO2
分子量:263.375
精确质量:263.189
Psa:43.7
Logp:2.7326

编号系统

MDL号:MFCD00871934

物化性质

外观与性状:白色结晶粉末
密度:1.115 g/cm3
沸点:403.8ºC at 760 mmHg
熔点:208-213ºC
闪点:193.2ºC
折射率:1.573
储存条件:-20ºC Freezer

安全信息

海关编码:2922509090
危险性描述:H225; H301 + H311 + H331; H370
危险标志:GHS02, GHS06, GHS08
信号词:Danger
危险性防范说明:P210; P280; P302 + P352 + P312; P304 + P340 + P312; P370 + P378; P403 + P235

生产方法及用途

合成路线

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图谱

13C NMR : Predict


1H NMR : Predict


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