化学科研者一站式服务平台


  • 10,11-二氢-10-羟基卡马西平

    licarbazepine

化合物简介

Licarbazepine is a voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects that is related to oxcarbazepine. It is an active metabolite of oxcarbazepine. In addition, an isomer of licarbazepine, eslicarbazepine ((S)-(+)-licarbazepine), is an active metabolite of eslicarbazepine acetate. Oxcarbazepine and eslicarbazepine acetate are inactive on their own, and behave instead as prodrugs to licarbazepine and eslicarbazepine, respectively, to produce their therapeutic effects.

基本信息

CAS:29331-92-8
中文别名:利卡西平;
英文别名:10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide,Licarbazepine;Licarbazepine,10,11-Dihydro-10-hydroxy-5H-dibenz(Z)[b,f]azepin-5-carboxamide;10,11-Dihydro-10-hydroxy Carbamazepine;10,11-Dihydro-10-hydroxycarbamazepine;
分子式:C15H14N2O2
分子量:254.284
精确质量:254.106
Psa:66.56
Logp:3.2582

编号系统

UNII:XFX1A5KJ3V

物化性质

密度:1.336g/cm3
沸点:431.3ºC at 760mmHg
熔点:186-189ºC
闪点:214.6ºC
折射率:1.677
蒸汽压:3.33E-08mmHg at 25°C

安全信息

海关编码:2933990090

生产方法及用途

合成路线

上游原料

下游产品

图谱

Predict 1H proton NMR


13C NMR : Predict


1H NMR : Predict


加载中...