N,O-Bis(trimethylsilyl)trifluoroacetamide (BSTFA) is a chemical compound that is used to derivatise labile groups such as hydroxyl on other chemicals, with the more stable trimethylsilyl group, which protects the labile group and allows the compound to be used for analytical purposes or as a chemical reagent for synthesis of more complex molecules. Siloxanes are usually more volatile than the corresponding hydroxyl compounds, and thus can be analyzed with gas chromatography better than the parent compound.

CAS：25561-30-2
中文别名：BSTFA,衍生化级;N,O-双(三甲基硅基)三氟乙酰胺;双(三甲基硅基)三氟乙酰胺;
英文别名：N,O-bis-TMS-trifluoroacetamide;8 Reaction vial,capacity;N,O-BSTFA;bstfa + tmcs;BSTFA;N,O-Bis(trimethylsilyl)trifluoroacetamide Kit BSTFA 1 mL ×Bis(trimethylsilyl);REGISIL RC-3;REGISIL RC-2;REGISIL RC-1;Bis(trimethylsilyl)trifluoroacetamide;bstfa kit;REGISIL(R) RC-1;
分子式：C8H18F3NOSi2
分子量：257.401
精确质量：257.088
Psa：21.59
Logp：3.6336

EINECS号：247-103-9
MDL号：MFCD00008269
BRN号：3607620

外观与性状：透明至淡黄色透明液体
密度：0.97g/mL(lit.)
沸点：45-50°C14mm Hg(lit.)
熔点：-10°C
闪点：75°C
折射率：n20/D 1.384(lit.)
水溶解性：hydrolyses
稳定性：Stable under normal temperatures and pressures.
储存条件：2-8ºC
蒸汽压：0.193mmHg at 25°C

安全说明：S26-S36/37/39-S45-S16
危险类别码：R10; R34
WGK Germany：3
危险品运输编码：UN 2924 3/PG 3
海关编码：29310095
危险类别：3
包装等级：III
危险品标志：C
危险性描述：H225; H302; H314
信号词：Danger
危险性防范说明：P210; P280; P305 + P351 + P338; P310
危险标志：GHS02, GHS05, GHS07
补充危害声明：对呼吸道有腐蚀性，与水剧烈反应。

用途
医药中间体。