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  • 匹罗卡品

    (+)-pilocarpine

化合物简介

Pilocarpine is a drug used to treat dry mouth and glaucoma. It is a parasympathomimetic alkaloid obtained from the leaves of tropical South American shrubs from the genus Pilocarpus. It is a non-selective muscarinic receptor agonist in the parasympathetic nervous system, which acts therapeutically at the muscarinic acetylcholine receptor M3 due to its topical application, e.g., in glaucoma and xerostomia.

基本信息

CAS:92-13-7
中文别名:毛果云香碱;毛果芸香碱;
英文别名:ocusertp20;PILOCARPINE;2(3H)-Furanone, 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-, (3S-cis)-;pilokarpol;Pilocarpol;Ocucarpine;Ocusert;actone;Syncarpine;Pilokarpin;Pilocarpin;
分子式:C11H16N2O2
分子量:208.257
精确质量:208.121
Psa:44.12
Logp:1.1618

编号系统

UNII:01MI4Q9DI3

物化性质

密度:1.22 g/cm3
沸点:260ºC at 5 MM HG (PARTIALºCONVERSION TO ISOPILºCARPINE)
闪点:215ºC

安全信息

安全说明:S25; S45
危险类别码:R26/28
危险品运输编码:UN 1544
危险类别:6.1(b)
包装等级:III
危险品标志:T+

生产方法及用途

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上游原料

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图谱

Predict 1H proton NMR


13C NMR : Predict


1H NMR : Predict


Mass spectrum (electron ionization)


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