化学科研者一站式服务平台


  • 顺-二十碳五烯酸乙酯

    ethyl (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate

化合物简介

Ethyl eicosapentaenoic acid (E-EPA, icosapent ethyl) is a derivative of the omega-3 fatty acid eicosapentaenoic acid (EPA) that is used in combination with changes in diet to lower triglyceride levels in adults with severe (≥ 500 mg/dL) hypertriglyceridemia. This was the second class of fish oil-based drug to be approved for use as a drug and was approved by the FDA in 2012. These fish oil drugs are similar to fish oil dietary supplements but the ingredients are better controlled and have been tested in clinical trials.

基本信息

CAS:86227-47-6
中文别名:cis-5,8,11,14,17-二十碳五烯酸乙酯;顺-5,8,11,14,17-十二碳五烯酸乙酯;
英文别名:Eicosapentaenoic Acid ethyl este;OMEGA-3-ACID ESTERS (EPA shown);(Z,Z,Z,Z,Z)-5,8,11,14,17-EICOSAPENTAENOIC ACID ETHYL ESTER;CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID ETHYL ESTER;ALL CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID ETHYL ESTER;Ethyl all cis-5,8,11,14,17-Icosapentaenoate;ALL CIS-5,8,11,14,17-EICOSAPENTANOIC ACID ETHYL ESTER;Eicosapentaenoic Acid ethyl ester;Eicosapentaenoic acid-D5 ethyl ester;Ethyl all cis-5,8,11,14,17-Eicosapentaenoate;
分子式:C22H34O2
分子量:330.504
精确质量:330.256
Psa:26.3
Logp:6.4712

编号系统

UNII:6GC8A4PAYH

物化性质

密度:0.91 g/cm3
储存条件:Refrigerator

安全信息

安全说明:S24/25
海关编码:2916190090

生产方法及用途

合成路线

  • 参考文献

    Takahashi, Yoshinori; Tanaka, Kaori; Murakami, Mototake; Kawanari, Masami; Kawasaki, Yoshihiro; et al. Bioscience, Biotechnology, and Biochemistry, 1995 , vol. 59, # 5 p. 809 - 812

上游原料

下游产品

图谱

13C NMR : Predict


加载中...