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  • ?9,11-去氢-17alpha-氰基甲基雌二醇

    17α-Cyanomethylestra-1,3,5(10),9(11)-tetraen-3,17β-diol

化合物简介

∆9,11-Dehydro-17α-cyanomethyl estradiol is a metabolite of progestin dienogest, and is currently being investigated for progesterone-receptor binding, progestational, antiprogestational, estrogenic and antigonadotropic activities for the inhibition of fertility. It is also being considered a novel treatment for heavy menstrual bleeding.

基本信息

CAS:86153-38-0
中文别名
英文别名:9,11-Dehydro-17a-cyanomethyl Estradiol;9,11-Dehydro-17Alpha-cyanomethyl Estradiol;17α-cyanomethyl-1,3,5(10),9(11)-estratetraene-3,17-diol;
分子式:C20H23NO2
分子量:309.402
精确质量:309.173
Psa:64.25
Logp:3.80278

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物化性质

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生产方法及用途

合成路线

  • 参考文献

    Hobe, G.; Schoen, R.; Frankenberg, G.; Schade, W.; Schubert, K. Steroids, 1983 , vol. 41, # 1 p. 23 - 34

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