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化合物简介

Dienogest is a steroidal progestin of the 19-nortestosterone group. It is available for use as an oral contraceptive in combination with ethinylestradiol. The drug also has antiandrogenic activity and as a result can improve androgenic symptoms. Dienogest is a non-ethinylated progestin which is structurally related to testosterone. It is given in isolation is available for the treatment of endometriosis under the trade name Visanne.

基本信息

CAS:65928-58-7
中文别名:地诺孕素;
英文别名:Dinagest;Dienogestril;[14C]-Dienogest;17a-Cyanomethyl-17-hydroxyestra-4,9-dien-3-one;STS 557;Dienogest;17a-CyanoMethyl-17b-hydroxyestra-4,9-dien-3-one;Dienogestrel;[3H]-Dienogest;Endometrion;
分子式:C20H25NO2
分子量:311.418
精确质量:311.189
Psa:61.09
Logp:3.83718

编号系统

UNII:46M3EV8HHE

物化性质

外观与性状:淡黄色固体
密度:1.2 g/cm3
沸点:549ºC at 760 mmHg
熔点:210-214ºC
闪点:285.8ºC
折射率:1.589
储存条件:-20ºC Freezer

安全信息

危险性描述:H361
信号词:Warning
危险性防范说明:P280
危险标志:GHS08

生产方法及用途

合成路线

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


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