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化合物简介
(R)-Laudanosine is an isomer of (S)-Laudanosine, a metabolite of the neuromuscular-blocking drugs Atracurium and Cisatracurium with potentially toxic systemic effects. It crosses the blood-brain barrier and may cause excitement and seizure activity.
基本信息
CAS：85-63-2
中文别名：
英文别名：N-methyl-1,2-dihydropapaverine;(R)-1-(3\',4\'-dimethoxybenzyl)-2-methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline;(+)-(R)-laudanosine;Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (R)-;Acetoacetic acid, 2,2-dichloro-;(R)-Laudanosine;(-)-(1R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline;
分子式：C21H27NO4
分子量：357.443
精确质量：357.194
Psa：40.16
Logp：3.4306
中文别名：
英文别名：N-methyl-1,2-dihydropapaverine;(R)-1-(3\',4\'-dimethoxybenzyl)-2-methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline;(+)-(R)-laudanosine;Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (R)-;Acetoacetic acid, 2,2-dichloro-;(R)-Laudanosine;(-)-(1R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline;
分子式：C21H27NO4
分子量：357.443
精确质量：357.194
Psa：40.16
Logp：3.4306
编号系统
物化性质
安全信息
生产方法及用途
合成路线
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参考文献
Comins, Daniel L.; Thakker, Paresh M.; Baevsky, Matthew F.; Badawi, Mohamed M. Tetrahedron, 1997 , vol. 53, # 48 p. 16327 - 16340
