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化合物简介
Laudanosine or N-methyltetrahydropapaverine is a recognized metabolite of atracurium and cisatracurium. Laudanosine decreases the seizure threshold, and thus it can induce seizures if present at sufficient threshold concentrations; however such concentrations are unlikely to be produced consequent to chemodegradable metabolism of clinically administered doses of cisatracurium or atracurium.
基本信息
CAS:2688-77-9
中文别名:
英文别名:Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (S)-;(1S)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline;
分子式:C21H27NO4
分子量:357.443
精确质量:357.194
Psa:40.16
Logp:3.4306
中文别名:
英文别名:Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (S)-;(1S)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline;
分子式:C21H27NO4
分子量:357.443
精确质量:357.194
Psa:40.16
Logp:3.4306
编号系统
EINECS号:220-253-2
物化性质
密度:1.111g/cm3
沸点:468.1ºC at 760mmHg
闪点:131.2ºC
沸点:468.1ºC at 760mmHg
闪点:131.2ºC
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict

1H NMR : Predict
