It inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent.

CAS：755037-03-7
中文别名：瑞格非尼;4-[4-({[4-氯-3-(三氟甲基)苯基]氨基甲酰}氨基)-3-氟苯氧基]-N-甲基吡啶-2-甲酰胺;
英文别名：4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide;4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide;4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide;Stivarga®;BAY 73-4506;
分子式：C21H15ClF4N4O3
分子量：482.815
精确质量：482.077
Psa：92.35
Logp：6.2257

UNII：24T2A1DOYB

密度：1.491 g/cm3
沸点：513.4ºC at 760 mmHg
闪点：264.3ºC