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  • BOC-L-天冬酰胺

    Nα-t-butoxycarbonyl-L-asparagine

化合物简介

Nα-Boc-L-asparagine is an N-Boc-protected form of L-Asparagine. L-Asparagine was first isolated by Robiquet and Vauquelin from asparagus juice (a high source of L-asparagine). L-Asparagine is often incorporated into proteins, and is a basis for some cancer therapies as certain cancerous cells require L-asparagine for growth.

基本信息

CAS:7536-55-2
中文别名:Nα-(叔丁氧羰基)-L-天冬酰胺;N-(Alpha)-Boc-L-天冬酰氨酸;N-叔丁氧羰基-L-天冬酰胺;叔丁氧羰基-天冬酰胺;叔丁氧羰基-L-天冬酰胺;Nα-Boc-L-天冬酰胺;Boc-天冬酰胺;
英文别名:N-Boc-Asparagine;Boc-L-Asn-OH;tert-Butoxycarbonylasparagine;Boc-Asn-OH;N-(tert-Butoxycarbonyl)-L-asparagine;(2S)-4-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxobutanoic acid;N(alpha)-t-butoxycarbonyl-L-asparagine;BOC-ASPARAGINE;N-BOC-L-asparagine;Nalpha-Boc-L-asparagine;Nalpha-(tert-Butoxycarbonyl)-L-asparagine;Boc-Asn;Boc-L-asparagine;
分子式:C9H16N2O5
分子量:232.234
精确质量:232.106
Psa:118.72
Logp:0.9309

编号系统

MDL号:MFCD00038152

物化性质

外观与性状:白色至灰白色结晶粉末
密度:1.253g/cm3
沸点:481.7ºC at 760 mmHg
熔点:170-175ºC
闪点:245.1ºC
稳定性:Stable at room temperature in closed containers under normal storage and handling conditions.
储存条件:-20ºC

安全信息

安全说明:S22-S24/25
危险类别码:R20/21/22
WGK Germany:3
海关编码:2924199090

生产方法及用途

用途
用于多肽合成,用作氨基酸保护单体。

合成路线

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


13C NMR : in DMSO-d6


1H NMR : 400 MHz in DMSO-d6


Mass


IR : KBr disc


IR : nujol mull


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