Isosorbide is a heterocyclic compound that is derived from glucose. Isosorbide and its two isomers, namely isoidide and isomannide, are 1,4:3,6-dianhydrohexitols. It is a white solid that is prepared from the double dehydration of sorbitol. Isosorbide is a non-toxic diol produced from biobased feedstocks, that is biodegradable and thermally stable. It is used in medicine and has been touted as a potential biofeedstock.

CAS：652-67-5
中文别名：甘宝素.氯咪巴唑.二唑丁酮;1,4:3,6-二脱水-D-葡萄糖醇;(3S,3AR,6R,6AR)-六氢-[3,2-B]呋喃-3,6-二醇;
英文别名：isobide;dianhydro-D-glucitol;Isosorbid;at101;1,4:3,6-dianhydrogluticol;dianhydro-D-sorbitol;1,4:3,6-dianhydro-D-glucitol;1,4:3,6-dianhydro-D-sorbitol;D-ISOSORBIDE;devicoran;IsMotic;hydronol;
分子式：C6H10O4
分子量：146.141
精确质量：146.058
Psa：58.92
Logp：-1.4942

MDL号：MFCD00064827

外观与性状：灰白色至淡黄色或米色晶体
密度：1.475 g/cm3
沸点：372.1ºC at 760 mmHg
熔点：60-63°C(lit.)
折射率：45 ° (C=5, H2O)
储存条件：Refrigerator

RTECS号：LZ4380000
安全说明：S24/25
WGK Germany：2
危险类别码：R22
海关编码：2932999099

用途
本品是山梨醇的脱水衍生物，为一口服渗透性脱水利尿药，作用机制类似于静注甘露醇和山梨醇。通过提高血浆渗透压，导致组织内(包括眼、脑、脑脊液等)水分进入血管内，从而减轻组织水肿，降低眼内压、颅内压和脑脊液容量及其压力。可用作医药中间体,合成塑料树脂添加剂,饲料添加剂。