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  • 氯吡拉敏

    N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine

化合物简介

Chloropyramine is a classical (\"old\" or first generation) antihistamine drug approved in some Eastern European countries (like Russia) for the treatment of allergic conjunctivitis, allergic rhinitis, bronchial asthma, and other atopic (allergic) conditions. Related indications for clinical use include angioedema (Quincke's edema), allergic reactions to insect bites, food and drug allergies, and anaphylactic shock.

基本信息

CAS:59-32-5
中文别名:氯吡胺;2-[(4-氯苄基)[2-(二甲基氨基)乙基]氨基]吡啶;
英文别名:Chlorpyramine;Chloropyramine;Halopyramine;N-(4-Chlor-benzyl)-N\',N\'-dimethyl-N-[2]pyridyl-aethylendiamin;Anaphylline;Avapena;Chlorpyraminum;Synpen;Suprastin;N-[(4-chlorophenyl)methyl]-N\',N\'-dimethyl-N-2-pyridinyl-1,2-ethanediamine;N-[(4-chlorophenyl)methyl]-N-[2-(dimethylamino)ethyl]pyridin-2-amine;N-(4-chloro-benzyl)-N\',N\'-dimethyl-N-[2]pyridyl-ethylenediamine;Chlorneoantergan;Synopen;N-(4-Chlor-benzyl)-N\',N\'-dimethyl-N-<2>pyridyl-ethylendiamin;
分子式:C16H20ClN3
分子量:289.803
精确质量:289.135
Psa:19.37
Logp:3.3032

编号系统

UNII:2K3L8O9SOV

物化性质

密度:1.158g/cm3
沸点:413.5ºC at 760 mmHg
闪点:203.9ºC
折射率:1.6

安全信息

生产方法及用途

合成路线

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图谱

13C NMR : Predict


1H NMR : Predict


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