2-Aminoethoxydiphenyl borate (2-APB) is a chemical that acts to inhibit both IP3 receptors and TRP channels (although it activates TRPV1, TRPV2, & TRPV3 at higher concentrations). In research it is used to manipulate intracellular release of calcium ions (Ca2+) and modify TRP channel activity, although there its lack of specific effects make it less than ideal under some circumstances. Additionally, there is evidence that 2-APB acts directly to inhibit gap junctions made of connexin26 or connexin32. Increasing evidence showed that 2-APB is a powerful modifier of store-operated calcium channels (SOC) function, low concentration of 2-APB can enhance SOC while high concentration induces a transient increase followed by complete inhibition.

CAS：524-95-8
中文别名：2-氨基乙基二苯硼酸酯;2-氨基乙酯二苯基硼酸;二苯;二苯基硼酸-2-氨基乙酯;2-氨基乙基联苯基硼酸酯;二苯硼酸2-氨基乙酯;
英文别名：(2-Aminoethoxy)diphenylborane;Diphenylborinic Acid 2-Aminoethyl Ester;2-diphenylboranyloxyethanamine;2-Aminoethoxydiphenyl borate,2-APB,2-Aminoethyl diphenyl borate;2-Aminoethyl diphenylborinate;
分子式：C14H16BNO
分子量：225.094
精确质量：225.132
Psa：35.25
Logp：1.4679

EINECS号：208-366-5
MDL号：MFCD00014823

外观与性状：白色
密度：1.04 g/cm3
沸点：325.3ºC at 760 mmHg
熔点：192-194°C(lit.)
闪点：150.6ºC
折射率：1.559
储存条件：2-8ºC

RTECS号：ED6150000
安全说明：S22-S24/25
WGK Germany：3
危险类别码：R36/37/38
海关编码：2931900090
危险品标志：Xn