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  • 1,5-dimethyl-2-phenylpyrazol-3-one;2,2,2-trichloroethane-1,1-diol (1:2)

    1,5-dimethyl-2-phenylpyrazol-3-one,2,2,2-trichloroethane-1,1-diol

化合物简介

Dichloralphenazone is a 1:2 mixture of antipyrine with chloral hydrate. In combination with paracetamol and isometheptene, it is the active ingredient of medications for migraine and vascular (tension) headaches, including Epidrin and Midrin. Performance impairments are common with this drug and caution is advised, for example when driving motor vehicles. Additional uses of dichloralphenazone include sedation for the treatment of short-term insomnia, although there are probably better drug choices for the treatment of insomnia.

基本信息

CAS:480-30-8
中文别名
英文别名:Kloralfenazon;Sominat;Dichloralantipyrin;Sedor;Dormuphar;dichloralphenazone;Welldorm;Dichloralantipyrine;Ibiodorm;
分子式:C15H18Cl6N2O5
分子量:519.032
精确质量:515.935
Psa:107.85
Logp:2.819

编号系统

UNII:YYX637R279

物化性质

沸点:319ºC at 760 mmHg
蒸汽压:0.000348mmHg at 25°C

安全信息

生产方法及用途

合成路线

  • 参考文献

    Behal; Choay Annales de Chimie (Cachan, France), 1892 , vol. <6>27, p. 320

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


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