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化合物简介

Felinine, also known as (R)-2-amino-3-(4-hydroxy-2-methylbutan-2-ylthio)propanoic acid, is a chemical compound and amino acid found in cat urine and a precursor via microbial lyase of the putative cat pheromone and thiol called 3-mercapto-3-methylbutan-1-ol (MMB). Felinine is excreted by selected Felidae species including bobcats, Chinese desert cats, the kodkod, and domestic cats. Felinine synthesis occurs in the liver through a condensation reaction of glutathione and isopentenyl pyrophosphate to form 3-mercaptobutanolglutathionine (3-MBG). In the kidney 3-MBG is hydrolysed and felinine partly acetylated. Cauxin assists in the hydrolysis of the dipeptide (felinylglycine) to increase the concentration of urinary felinine. Urine of domestic cats may contain a series of felinine-containing compounds including free felinine, acetylfelinine, felinylglycine and 3-MBG.

基本信息

CAS:471-09-0
中文别名:貓尿胺酸;
英文别名:l-Felinine;2-Amino-7-hydroxy-5,5-dimethyl-4-thiaheptanoic acid;Felinine;(2R)-2-amino-3-(4-hydroxy-2-methylbutan-2-yl)sulfanylpropanoic acid;
分子式:C8H17NO3S
分子量:207.29
精确质量:207.093
Psa:108.85
Logp:0.9928

编号系统

UNII:8V49J0ABL5

物化性质

密度:1.213g/cm3
沸点:359.6ºC at 760mmHg
熔点:162-164ºC
闪点:171.3ºC
折射率:1.54
储存条件:-20ºC Freezer, Under Inert Atmosphere
蒸汽压:1.28E-06mmHg at 25°C

安全信息

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