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  • 硝甲喹酮

    3-(2-methoxy-4-nitrophenyl)-2-methylquinazolin-4-one

化合物简介

Nitromethaqualone is an analogue of methaqualone that has similar sedative and hypnotic properties. It is significantly more potent (10x) compared to the parent compound; the typical dose is approximately 25mg. However, the aromatic nitro group is metabolised to the corresponding aniline, which proved to be a mutagen. As a consequence, nitromethaqualone was not developed further due to toxicity concerns.

基本信息

CAS:340-52-3
中文别名
英文别名:nitromethaqualone;Nitrometaqualone;CHI 26;Parnox;
分子式:C16H13N3O4
分子量:311.292
精确质量:311.091
Psa:89.94
Logp:3.1341

编号系统

UNII:7G855468ZM

物化性质

密度:1.36g/cm3
沸点:528ºC at 760 mmHg
闪点:273.1ºC
折射率:1.651

安全信息

海关编码:2933990090

生产方法及用途

合成路线

上游原料

下游产品

图谱

1H NMR : Predict


13C NMR : Predict


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