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化合物简介
Nitromethaqualone is an analogue of methaqualone that has similar sedative and hypnotic properties. It is significantly more potent (10x) compared to the parent compound; the typical dose is approximately 25mg. However, the aromatic nitro group is metabolised to the corresponding aniline, which proved to be a mutagen. As a consequence, nitromethaqualone was not developed further due to toxicity concerns.
基本信息
CAS:340-52-3
中文别名:
英文别名:nitromethaqualone;Nitrometaqualone;CHI 26;Parnox;
分子式:C16H13N3O4
分子量:311.292
精确质量:311.091
Psa:89.94
Logp:3.1341
中文别名:
英文别名:nitromethaqualone;Nitrometaqualone;CHI 26;Parnox;
分子式:C16H13N3O4
分子量:311.292
精确质量:311.091
Psa:89.94
Logp:3.1341
编号系统
UNII:7G855468ZM
物化性质
密度:1.36g/cm3
沸点:528ºC at 760 mmHg
闪点:273.1ºC
折射率:1.651
沸点:528ºC at 760 mmHg
闪点:273.1ºC
折射率:1.651
安全信息
海关编码:2933990090
生产方法及用途
合成路线
上游原料
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图谱
1H NMR : Predict

13C NMR : Predict
