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化合物简介

Pimethixene is an antihistamine and anticholinergic of the thioxanthene chemical class that is often used to treat hyperactivity, anxiety, sleep disorders, and allergy. It is also used for anesthesia and as a bronchodilator (to dilate the bronchi and bronchioles for more airflow).

基本信息

CAS:314-03-4
中文别名
英文别名:Calmixene;10-(1-methyl-4-piperidylidene)dibenzo[b,e]thiane;1-methyl-4-(9H-thioxanthen-9-ylidene)-piperidine;1-methyl-4-thioxanthen-9-ylidene-piperidine;Calmixen;9-(N-methyl-piperidyliden-4-yl)-thioxanthene;9-(N-methyl-piperidyliden-4)-thioxanthene;
分子式:C19H19NS
分子量:293.426
精确质量:293.124
Psa:28.54
Logp:4.6166

编号系统

UNII:T46J20J26F

物化性质

密度:1.192g/cm3
沸点:439.7ºC at 760mmHg
闪点:219.7ºC
折射率:1.661

安全信息

生产方法及用途

合成路线

  • 参考文献

    FMC CORPORATION Patent: WO2004/26030 A2, 2004 ; Location in patent: Page 31 ;

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图谱

13C NMR : Predict


1H NMR : Predict


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