N-Carbethoxy-4-piperidone is used in the preparation of 3-hydrazinopyridazines as antihypertensive agents as well as γ-carboline derivatives as potential serotonergic agents. N-Carbethoxy-4-piperidone is also an impurity of Loratadine.

CAS：29976-53-2
中文别名：4-氧代-1-哌啶羧酸乙酯;1-乙氧基羰基-4-哌啶酮;4-氧代-1-哌啶甲酸乙酯;1-乙氧羰基-4-哌啶酮;1-乙;N-乙氧甲酰基-4-哌啶酮;N-乙羧氧基-4-哌啶酮;
英文别名：N-carboethoxy-4-piperidinone;1-CARBETHOXY-4-PIPERIDONE;carbethoxy-4-piperidone;Ethyl 4-Oxo-1-piperidinecarboxylate;4-Oxo-1-piperidinecarboxylic Acid Ethyl Ester;4-oxo-piperidine-1-carboxylic acid ethyl ester;N-Carbethoxy-4-piperidon;1-ethoxycarbonyl-4-piperidinone;1-carboethoxy-4-piperidone;1-Carbethoxy-4-piperidone;AURORA KA-3057;Loratadine impurity H;ethyl 4-oxopiperidine-1-carboxylate;N-ETHOXYCARBONYL-4-PIPERIDONE;N-CARBOETHOXY-4-PIPERIDONE;1-Ethoxycarbonyl-4-piperidone;1-Carbethoxy-4-piperidone,1-Ethoxycarbonyl-4-piperidone,Ethyl 4-oxo-1-piperidinecarboxylate;1-Piperidinecarboxylic acid, 4-oxo-, ethyl ester;N-Carbithoxy-4-Piperidone;N-Carbethoxypiperidone;
分子式：C8H13NO3
分子量：171.194
精确质量：171.09
Psa：46.61
Logp：0.7457

MDL号：MFCD00006188

外观与性状：无色液体
密度：1.135g/mLat 25°C(lit.)
沸点：95-98 °C (1 mmHg)
闪点：190°F
折射率：n20/D 1.475(lit.)
水溶解性：slightly soluble
稳定性：Stable under normal temperatures and pressures.
储存条件：Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
蒸汽压：0.00574mmHg at 25°C

安全说明：S23-S24/25-S37/39-S26
危险类别码：R22; R36/38
WGK Germany：3
海关编码：2933399090
危险品标志：Xn

生产方法
1、五氟利多的中间体。 1、医药中间体
用途
1、医药中间体