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2-(1-(4-氯苯甲酰基)-5-甲氧基-2-甲基-1H-吲哚-3-基)-1-吗啉乙酮
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-1-morpholin-4-ylethanone
化合物简介
BML-190 (Indomethacin morpholinylamide) is a drug used in scientific research that acts as a selective CB2 inverse agonist. BML-190 is structurally derived from the NSAID indomethacin but has a quite different biological activity. The activity produced by this compound is disputed, with some sources referring to it as a CB2 agonist rather than an inverse agonist; this may reflect an error in classification, or alternatively it may produce different effects in different tissues, and more research is required to resolve this dispute.
基本信息
CAS：2854-32-2
中文别名：2-[1-(4-氯苯甲酰基)-5-甲氧基-2-甲基-1H-吲哚-3-基]-1-(4-吗啉基)乙酮;
英文别名：Lopac-I-151;Indomethacin Morpholinylamide;Tocris-1383;Indomethacin morpholinamide;Indomethacin morpholinylamide;2-Methyl-5-methoxy-3-indolyl-essigsaeure-amid;IMMA;Ethanone (2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-1-(4-morpholinyl);BML-190;
分子式：C23H23ClN2O4
分子量：426.893
精确质量：426.135
Psa：60.77
Logp：3.6394
中文别名：2-[1-(4-氯苯甲酰基)-5-甲氧基-2-甲基-1H-吲哚-3-基]-1-(4-吗啉基)乙酮;
英文别名：Lopac-I-151;Indomethacin Morpholinylamide;Tocris-1383;Indomethacin morpholinamide;Indomethacin morpholinylamide;2-Methyl-5-methoxy-3-indolyl-essigsaeure-amid;IMMA;Ethanone (2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-1-(4-morpholinyl);BML-190;
分子式：C23H23ClN2O4
分子量：426.893
精确质量：426.135
Psa：60.77
Logp：3.6394
编号系统
MDL号：MFCD01317813
物化性质
密度：1.31g/cm3
沸点：586.7ºC at 760mmHg
闪点：308.6ºC
折射率：1.624
储存条件：2-8ºC
蒸汽压：8.34E-17mmHg at 25°C
沸点：586.7ºC at 760mmHg
闪点：308.6ºC
折射率：1.624
储存条件：2-8ºC
蒸汽压：8.34E-17mmHg at 25°C
安全信息
WGK Germany：3
海关编码：2934999090
海关编码：2934999090
生产方法及用途
合成路线
上游原料
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图谱
Predict 1H proton NMR
