Lapatinib intermediate.

CAS：231278-20-9
中文别名：4-[3-氯-4-(3-氟苄氧基)苯胺基]-6-碘喹唑啉;4-[3-氯-4-(3-氟苄氧基)苯氨基]-6-碘喹唑啉;N-[3-氯-4-(3-氟苄氧基)苯基]-6-碘喹唑啉-4-胺;4-胺基-N-[3-氯-4-[(3-氟苄基)氧]苯基]-6-碘喹唑啉;
英文别名：N-{3-chloro-4-[(3-fluorophenyl)Methoxy]phenyl}-6-iodoquinazolin-4-aMine;Lapatinib Intermediate 2;[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl](6-iodoquinazol;N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methanesulphonyl) ethyl]amino}methyl)-2-furyl]-4-quinazolin amine ditosylate;(6-iodo-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-quinazolin-4-yl)amine;N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-iodoquinazolin-4-amine;N-{3-Chloro-4-[(3-fluorophenyl)-methoxy]-phenyl}-6-iodo-4-quinazolinamine;4-[3-Chloro-4-(3-fluorobenzyloxy)anilino]-6-iodoquinazoline;4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline;N-[3-chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodo-quinazolin-4yl-amine;N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-iodo-4-quinazolinamine;N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-iodoquinazolin-4-aMine;4-[3-Chloro-4-(3-fluorobenzyloxy)phenylaMino]-6-iodoquinazoline;N-[3-chloro-4-(3-fluorobenzyloxy)-phenyl]-6-iodoquinazolin-4-amine;6-Iodo-4-[3-chloro-4-(3-fluorobenzyloxy)anilino]quinazoline;N-[3-Chloro-4-(3-fluorobenzyloxy)-phenyl]-6-iodoquinazolin-4-amine;N-[3-chloro-4-(3-fluorobenzyloxy)phenylJ-6-iodoquinazolin-4-amine;[3-chloro-4-(3-fluorobenzyloxy)phenyl]-(6-iodoquinazolin-4-yl)amine;
分子式：C21H14ClFIN3O
分子量：505.711
精确质量：504.985
Psa：47.04
Logp：6.4225

MDL号：MFCD09998827

外观与性状：黄色固体
密度：1.691 g/cm3
沸点：581.326ºC at 760 mmHg
熔点：222-224°C
闪点：305.375ºC
折射率：1.724
蒸汽压：0mmHg at 25°C

安全说明：S26; S36/37/39
危险类别码：R36/37/38
海关编码：2933990090
危险品标志：Xi

用途
拉帕替尼中间体。