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    Dexmedetomidine

化合物简介

Dexmedetomidine, sold under the trade names Precedex among others, is an anxiolytic, sedative, and analgesic medication. Similar to clonidine, it is an agonist of α2-adrenergic receptors in certain parts of the brain. Dexmedetomidine is notable for its ability to provide sedation without risk of respiratory depression (unlike other commonly used sedatives such as propofol, fentanyl, and midazolam) and can provide cooperative or semi-arousable sedation. Dexmedetomidine hydrochloride is also used in veterinary medicine for dogs and cats. The drug was developed by Orion Pharma.

基本信息

CAS:113775-47-6
中文别名
英文别名:5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole;dexmedetomidine;Dexmedetomidina;(S)-medetomidine;Dexmedetomidinum;Precedex;
分子式:C13H16N2
分子量:200.28
精确质量:200.131
Psa:28.68
Logp:3.1783

编号系统

UNII:67VB76HONO

物化性质

密度:1.053g/cm3
沸点:381.9ºC at 760mmHg
闪点:191.3ºC
折射率:1.569
蒸汽压:1.08E-05mmHg at 25°C

安全信息

海关编码:2933290090

生产方法及用途

合成路线

上游原料

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图谱

13C NMR : Predict


1H NMR : Predict


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