K252a is an alkaloid isolated from Nocardiopisis sp. soil fungi. This staurosporine analog is a highly potent cell permeable inhibitor of CaM kinase and phosphorylase kinase (IC50 = 1.8 and 1.7 nmol/L, respectively). At higher concentrations it is also an efficient inhibitor of serine/threonine protein kinases (IC50 of 10 to 30 nmol/L).

CAS：99533-80-9
中文别名：
英文别名：K-252A,NOCARDIOPSIS SP;antibioticsf2370;PROTEIN KINASE INHIBITOR FROM NORCARDIOP SIS SP.;PROTEIN KINASE INHIBITOR K-252A;antibiotick252a;sf2370;K252a;PROTEIN KINASE INHIBITOR;
分子式：C27H21N3O5
分子量：467.473
精确质量：467.148
Psa：94.72
Logp：3.9839

UNII：IV7H45AM5B

密度：1.67g/cm3
沸点：685.3ºC at 760mmHg
闪点：368.2ºC
折射率：1.841
储存条件：-20ºC

安全说明：S22; S24/25
危险品标志：Xi
危险性描述：H360D; H371
信号词：Danger
危险标志：GHS08
危险性防范说明：P201; P260; P308 + P311