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  • 苯并[b]噻吩-2-基甲酮

    bis(1-benzothiophen-2-yl)methanone

化合物简介

Benzo[b]thien-2-yl ketone is an impurity of Zileuton, an inhibitor of 5-lipoxygenase that is used to treat patients with asthma. Benzo[b]thien-2-yl ketone is used as a reagent to synthesize Bis(1H-2-indolyl)methanone, compounds that inhibit the activity of growth factor receptor kinase. Benzo[b]thien-2-yl ketone is also used as a reagent to prepare annulated oligothiophenes, compounds that are used in organic light-emitting devides (OLEDs).

基本信息

CAS:97978-07-9
中文别名
英文别名:Methanone,bis(benzo[b]thien-2-yl);Bis(1H-2-indolyl)methanone 18;bis(benzothiophen-2-yl)methanone;Bis--keton;di(2-benzothienyl) ketone;di-benzo[b]thiophen-2-yl-methanone;
分子式:C17H10OS2
分子量:294.391
精确质量:294.017
Psa:73.55
Logp:5.347

编号系统

物化性质

安全信息

生产方法及用途

合成路线

  • 参考文献

    Mahboobi, Siavosh; Teller, Steffen; Pongratz, Herwig; Hufsky, Harald; Sellmer, Andreas; Botzki, Alexander; Uecker, Andrea; Beckers, Thomas; Baasner, Silke; Schaechtele, Christoph; Ueberall, Florian; Kassack, Matthias U.; Dove, Stefan; Boehmer, Frank-D. Journal of Medicinal Chemistry, 2002 , vol. 45, # 5 p. 1002 - 1018

上游原料

下游产品

图谱

1H NMR : Predict


13C NMR : Predict


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