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  • 二氟-羟基-(亚异丙基二氧丙基)-丙酸乙酯

    Ethyl (3R,S)-2,2-difluoro-3-hydroxy-3-(2,2-dimethyldioxolan-4-yl)propionate

化合物简介

Intermediate in the preparation of ribose sugar derivatives.

基本信息

CAS:95058-92-7
中文别名:(3R,S)-2,2-二氟-3-羟基-(2,2-二甲基二氧环戊-4-基)丙酸乙酯;吉西他滨中间体T3;(3R,S)-2,2-二氟-3-羟基-3-(2,2-二甲基二氧环戊-4-基)丙酸乙酯;乙基-3-(2,2-二甲基-1,3-二氧戊烷-4-基)-2,2-二氟-3-羟基丙酸;(R)-3-((R)-2,2-二甲基-1,3-二氧五环-4-基)-2,2-二氟-3-羟基-丙酸乙酯;
英文别名:ethyl 2,2-difluoro-3(R)-hydroxy-3-((R)-2,2-dimethyldioxolan-4-yl)propionate;3-(2,2-Dimethyl[1,3]dioxolan-4-yl)-2,2-difluora-3-hydroxy-propionic acid ethyl ester;ethyl (3R)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-difluoro-3-hydroxypropanoate;Ethyl(3RS)-2,2-Difluoro-3-(2,2-Dimethylioxolan-4-yl)Propionate;Ethyl(3R,S)-2,2-difluoro-3-hydroxy-3-(2,2-dimethyldioxolan-4-yl)propionate;(erytro) ethyl-3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-difluoro-3-hydroxy propionate;D-ERYTHRO-PENTONIC ACID,2-DEOXY-2,2-DIFLUORO-4,5-O-(1-METHYLETHYLIDENE)-,ETHYL ESTER;Ethyl(3RS)-2,2-Difluoro-3-(2,2-dimethyldioxolan-4-yl)propionate;ethyl (R)-2,2-difluoro-3-hydroxy-3-((R)-2,2-dimethyl-[1,3]dioxoran-4-yl)propionate;D-erythro-Pentonic acid,2-deoxy-2,2-difluoro-4,5-O-(1-methylethylidene)-,ethyl ester (9CI);(R)-ethyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-difluoro-3-hydroxypropanoate;2-Deoxy-2,2-difluoro-4,5-O-isopropylidene-D-erythro-pentonic Acid Ethyl Ester;ethyl 2,2-difluoro-3-hydroxy-3-(2,2-dimethyl-[1,3]dioxolan-4-yl)propionate;propionate (T3);ethyl (3R,4R)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-difluoro-3-hydroxypropanoate;2-DEOXY-2,2-DIFLUORO-4,5-O-(1-METHYLETHYLIDENE)-D-ERYTHROPENTONIC ACID ETHYL ESTER;ethyl (D-erythro)-3-(hydroxy)-2,2-difluoro-3-(2,2-dimethyldioxalane-4-yl)propionate;
分子式:C10H16F2O5
分子量:254.228
精确质量:254.097
Psa:64.99
Logp:0.6972

编号系统

MDL号:MFCD09031375

物化性质

密度:1.232g/cm3
沸点:338.388ºC at 760 mmHg
闪点:158.451ºC
折射率:1.428

安全信息

海关编码:2942000000

生产方法及用途

用途
吉西他滨中间体。

合成路线

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


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