HBTU (2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate) is a coupling reagent used in solid phase peptide synthesis. It was introduced in 1978 and shows resistance against racemization. It is used because of its mild activating properties.

CAS：94790-37-1
中文别名：苯并三氮唑-N,N,N’,N’-四甲基脲六氟磷酸酯;O-(苯并三唑-1-基)-N,N,N\',N\'-四甲基脲六氟磷酸盐;N,N,N\',N\'-四甲基-O-(苯并三氮唑-1-基)硫脲六氟磷酸盐;苯并三氮唑-N,N,N\',N\'-四甲基脲六氟磷酸酯;苯并三氮唑-N,N,N\',N\'-四甲基脲六氟磷酸酯(HBTU);苯并三氮唑-N,N,N\',N\'-四甲基脲六氟磷酸盐;HBTU/苯并三氮唑-N,N,N\',N\'-四甲基脲六氟磷酸盐;
英文别名：[benzotriazol-1-yloxy(dimethylamino)methylidene]-dimethylazanium,hexafluorophosphate;
分子式：C11H16F6N5OP
分子量：379.242
精确质量：379.1
Psa：59.78
Logp：3.432

UNII：X5I03TZQ8D

外观与性状：白色结晶粉末
熔点：200°C (dec.)(lit.)
闪点：200°C
稳定性：Stable. Incompatible with oxidizing agents.
储存条件：2-8ºC

安全说明：S26-S36/37/39
WGK Germany：3
危险类别码：R20/21/22; R36/37/38
危险品标志：Xn