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化合物简介
Tripelennamine (sold as Pyribenzamine by Novartis) is a drug that is used as an antipruritic and first-generation antihistamine. It can be used in the treatment of asthma, hay fever, rhinitis and urticaria, but is now less common as it has been replaced by newer antihistamines.
基本信息
CAS：91-81-6
中文别名：
英文别名：Pyrinamine base;tripelennamine;N-benzyl-N\',N\'-dimethyl-N-pyridin-2-yl-ethane-1,2-diamine;N-benzyl-N\',N\'-dimethyl-N-[2]pyridyl-ethylenediamine;Tripelennamin;Benzoxale;Tripelennamina;1,2-Ethanediamine, N,N-dimethyl-N‘-(phenylmethyl)-N‘-2-pyridinyl-;Piribenzil;Pyribenzamine;Tonaril;Resistamine;Cizaron;tripelenamin;
分子式：C16H21N3
分子量：255.358
精确质量：255.174
Psa：19.37
Logp：2.6498
中文别名：
英文别名：Pyrinamine base;tripelennamine;N-benzyl-N\',N\'-dimethyl-N-pyridin-2-yl-ethane-1,2-diamine;N-benzyl-N\',N\'-dimethyl-N-[2]pyridyl-ethylenediamine;Tripelennamin;Benzoxale;Tripelennamina;1,2-Ethanediamine, N,N-dimethyl-N‘-(phenylmethyl)-N‘-2-pyridinyl-;Piribenzil;Pyribenzamine;Tonaril;Resistamine;Cizaron;tripelenamin;
分子式：C16H21N3
分子量：255.358
精确质量：255.174
Psa：19.37
Logp：2.6498
编号系统
UNII：3C5ORO99TY
物化性质
外观与性状：油性液体
沸点：185 - 190ºC at 1.7 mm Hg
稳定性：Stable. Incompatible with strong oxidizing agents.
沸点：185 - 190ºC at 1.7 mm Hg
稳定性：Stable. Incompatible with strong oxidizing agents.
安全信息
生产方法及用途
合成路线
-
参考文献
Hamid, M. Haniti S. A.; Allen, C. Liana; Lamb, Gareth W.; Maxwell, Aoife C.; Maytum, Hannah C.; et al. Journal of the American Chemical Society, 2009 , vol. 131, p. 1766 - 1774
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
Mass spectrum (electron ionization)
