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化合物简介

Fostamatinib is an experimental drug candidate for the treatment of a variety of diseases, originally developed by Rigel Pharmaceuticals. The drug is administered orally as a disodium salt, and is a prodrug of the active compound tamatinib (R-406), which is an inhibitor of the enzyme spleen tyrosine kinase (Syk), hence it is an syk inhibitor.

基本信息

CAS:901119-35-5
中文别名
英文别名:R788 compound;Fostamatinib;Fostamatinib (R788);
分子式:C23H26FN6O9P
分子量:580.46
精确质量:580.148
Psa:199.76
Logp:2.6544

编号系统

MDL号:MFCD16628163

物化性质

密度:1.5±0.1g/cm3
沸点:814.2±75.0°Cat760mmHg
闪点:446.2±37.1°C
蒸汽压:0.0±3.1mmHgat25°C
折射率:1.629
储存条件:-20°C

安全信息

生产方法及用途

合成路线

上游原料

下游产品

图谱

1H NMR : Predict


13C NMR : Predict


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