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化合物简介
Fostamatinib is an experimental drug candidate for the treatment of a variety of diseases, originally developed by Rigel Pharmaceuticals. The drug is administered orally as a disodium salt, and is a prodrug of the active compound tamatinib (R-406), which is an inhibitor of the enzyme spleen tyrosine kinase (Syk), hence it is an syk inhibitor.
基本信息
CAS:901119-35-5
中文别名:
英文别名:R788 compound;Fostamatinib;Fostamatinib (R788);
分子式:C23H26FN6O9P
分子量:580.46
精确质量:580.148
Psa:199.76
Logp:2.6544
中文别名:
英文别名:R788 compound;Fostamatinib;Fostamatinib (R788);
分子式:C23H26FN6O9P
分子量:580.46
精确质量:580.148
Psa:199.76
Logp:2.6544
编号系统
MDL号:MFCD16628163
物化性质
密度:1.5±0.1g/cm3
沸点:814.2±75.0°Cat760mmHg
闪点:446.2±37.1°C
蒸汽压:0.0±3.1mmHgat25°C
折射率:1.629
储存条件:-20°C
沸点:814.2±75.0°Cat760mmHg
闪点:446.2±37.1°C
蒸汽压:0.0±3.1mmHgat25°C
折射率:1.629
储存条件:-20°C
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
1H NMR : Predict

13C NMR : Predict
