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  • 苯丁酰脲

    2-PHENYLBUTYRYLUREA

化合物简介

Pheneturide (INN, BAN) (brand names Benuride, Deturid, Pheneturid, Septotence, Trinuride), also known as phenylethylacetylurea (or ethylphenacemide), is an anticonvulsant of the ureide class. It is considered to be obsolete, and is now seldom used. It is marketed in Europe, including in Poland, Spain, and the United Kingdom. Pheneturide has a similar profile of anticonvulsant activity and toxicity relative to phenacemide, but is less toxic in comparison, despite still being a toxic drug. As such, it is only used in cases of severe epilepsy when other, less-toxic drugs have failed. Pheneturide inhibits the metabolism and thus increases the levels of other anticonvulsants, such as phenytoin.

基本信息

CAS:90-49-3
中文别名:乙苯乙酰脲;1-((乙基)苯乙酰)脲;Beta刴ethoxynaph-talene;
英文别名:Phenuride;Lircapyl;PHENETURIDE;S 46;Benuride;ETHYLPHENACEMIDE;PBU;
分子式:C11H14N2O2
分子量:206.241
精确质量:206.106
Psa:72.19
Logp:2.4663

编号系统

UNII:878CEJ4HGX

物化性质

密度:1.15g/cm3
折射率:1.547

安全信息

危险品运输编码:UN 3249
危险类别:6.1(b)
包装等级:III

生产方法及用途

合成路线

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


Mass spectrum (electron ionization)


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