tert-Butyl 4-Bromo-2-fluorobenzoate is an intermediate of enzalutamide. Enzalutamide is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to induce tumor cell apoptosis, and has no agonist activity. MDV 3100 is a candidate for the treatment of castration-resistant prostate cancer.

CAS：889858-12-2
中文别名：
英文别名：4-bromo-2-fluoro-benzoic acid tert-butyl ester;Tert-butyl 4-bromo-2-fluorobenzoate;
分子式：C11H12BrFO2
分子量：275.114
精确质量：274.0
Psa：26.3
Logp：3.5435

EINECS号：810-257-8

密度：1.394g/cm3
沸点：281ºC at 760 mmHg
闪点：123.7ºC
折射率：1.515

海关编码：2916399090