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  • 西那利定

    1-methyl-N-phenyl-N-(thiophen-2-ylmethyl)piperidin-4-amine

化合物简介

Thenalidine is an antihistamine with anticholinergic properties used as an antipruritic drug. It was withdrawn from the US, Canadian, and UK markets in 1963 due to a risk of neutropenia.

基本信息

CAS:86-12-4
中文别名
英文别名:N-Methyl-4-(N-thenyl-2-anilino)-piperidin;Tenalidina;Thenalidinum;Sandosten (4-Amino-1-methyl-N\'-phenyl-N\'-then-2-yl-piperidin-tartrat);Sanbosten;N-(1-methyl-[4]piperidyl)-N-[2]thienylmethyl-aniline;thenalidine;Tenalidina [INN-Spanish];4-Piperidinamine, 1-methyl-N-phenyl-N-(2-thienylmethyl)-;Thenophenopiperidine;Thenalidinum [INN-Latin];1-Methyl-4-N-2-thenylanilinopiperidine;1-Methyl-4-amino-N-phenyl-N-(2-thenyl)piperidine;Thenaldine;N-(1-Methyl-[4]piperidyl)-N-[2]thienylmethyl-anilin;1-Methyl-4--piperidin;
分子式:C17H22N2S
分子量:286.435
精确质量:286.15
Psa:34.72
Logp:3.7868

编号系统

UNII:6U94N2D00F

物化性质

密度:1.14g/cm3
沸点:413.9ºC at 760 mmHg
闪点:204.1ºC
折射率:1.619

安全信息

海关编码:2934999090

生产方法及用途

合成路线

上游原料

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图谱

13C NMR : Predict


1H NMR : Predict


Mass spectrum (electron ionization)


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