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化合物简介
Dotarizine is a drug used in the treatment of migraine, which acts as a calcium channel blocker, and also as an antagonist at the 5HT2A receptor, and to a lesser extent at the 5HT1A and 5HT2C receptors. The anti-migraine action is thought to be due to its action as a vasodilator, but it also has some anxiolytic effects and blocks amnesia produced by electroconvulsive shock in animals.
基本信息
CAS:84625-59-2
中文别名:
英文别名:DOTARIZINE;Dotarizinum;Dotarizina;
分子式:C29H34N2O2
分子量:442.592
精确质量:442.262
Psa:24.94
Logp:4.9494
中文别名:
英文别名:DOTARIZINE;Dotarizinum;Dotarizina;
分子式:C29H34N2O2
分子量:442.592
精确质量:442.262
Psa:24.94
Logp:4.9494
编号系统
物化性质
密度:1.122 g/cm3
沸点:557.4ºC at 760 mmHg
熔点:100-101ºC
闪点:147.9ºC
折射率:1.587
沸点:557.4ºC at 760 mmHg
熔点:100-101ºC
闪点:147.9ºC
折射率:1.587
安全信息
海关编码:2933599090
生产方法及用途
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图谱
13C NMR : Predict

1H NMR : Predict
