化学科研者一站式服务平台
-
N-[(1-乙基-2-吡咯烷基)甲基]-2-羟基-3-碘-6-甲氧基-苯甲酰胺
BENZAMIDE, N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-HYDROXY-3-IODO-6-METHOXY-
化合物简介
IBZM (abbreviation for iodobenzamide) is a chemical substance. Pharmaceutically it is a dopamine antagonist and it can be used by nuclear medicine physicians as a radioactive tracer for SPECT where the radioactive isotope is iodine-123 or iodine-125. The main purpose of a brain study with IBZM is the differentiation of Parkinson's disease from other neurodegenerative diseases such as Lewy Body dementia and multiple system atrophy.
基本信息
CAS：84226-06-2
中文别名：
英文别名：IBZM;(s)-benzamid;N-[[(2S)-1-Ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-3-iodo-6-methoxybenzamide;S-(-)-IBZM;IODOBENZAMIDE,(S)-(-)-3-IODO-2-HYDROXY-6-METHOXY-N[(1-ETHYL-2-PYRROLIDINYL)METHYL]BENZAMIDE;3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide;[123I]-IBZM;(S)-N-(1-ethylpyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxybenzamide;(s)-n-(1-ethyl-2-pyrrolidinyl)methyl-2-hydroxy-3-iodo-6-methoxybenzamide;(S)-(-)-3-iodo-2-hydroxy-6-methoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]benzamide;
分子式：C15H21IN2O3
分子量：404.243
精确质量：404.06
Psa：61.8
Logp：2.5483
中文别名：
英文别名：IBZM;(s)-benzamid;N-[[(2S)-1-Ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-3-iodo-6-methoxybenzamide;S-(-)-IBZM;IODOBENZAMIDE,(S)-(-)-3-IODO-2-HYDROXY-6-METHOXY-N[(1-ETHYL-2-PYRROLIDINYL)METHYL]BENZAMIDE;3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide;[123I]-IBZM;(S)-N-(1-ethylpyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxybenzamide;(s)-n-(1-ethyl-2-pyrrolidinyl)methyl-2-hydroxy-3-iodo-6-methoxybenzamide;(S)-(-)-3-iodo-2-hydroxy-6-methoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]benzamide;
分子式：C15H21IN2O3
分子量：404.243
精确质量：404.06
Psa：61.8
Logp：2.5483
编号系统
UNII：9J5D4ZN1JK
物化性质
外观与性状：暗黄色油状
密度：1.51 g/cm3
沸点：426.9ºC at 760 mmHg
闪点：212ºC
储存条件：2-8ºC
密度：1.51 g/cm3
沸点：426.9ºC at 760 mmHg
闪点：212ºC
储存条件：2-8ºC
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
