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  • 萘甲唑林

    2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole

化合物简介

Naphazoline (in the hydrochloride form) is the common name for 2-(1-naphthylmethyl)-2-imidazoline hydrochloride. It is a sympathomimetic agent with marked alpha adrenergic activity. It is a vasoconstrictor with a rapid action in reducing swelling when applied to mucous membrane. It acts on alpha-receptors in the arterioles of the conjunctiva to produce constriction, resulting in decreased congestion. It is an active ingredient in several over-the-counter formulations including Clear Eyes and Naphcon eye drops.

基本信息

CAS:835-31-4
中文别名:2-(1-萘甲)咪唑啉鹽酸鹽;2-(1-萘甲基)-4,5-二氢-1H-咪唑;萘达帕汀;
英文别名:Naphthizine;Antan;Clearine;Nafazolina;naphazoline;
分子式:C14H14N2
分子量:210.274
精确质量:210.116
Psa:24.39
Logp:2.1484

编号系统

UNII:H231GF11BV

物化性质

密度:1.15g/cm3
沸点:440.5ºC at 760 mmHg
熔点:254ºC
闪点:220.2ºC
折射率:1.64

安全信息

RTECS号:NJ4375000
安全说明:S45
WGK Germany:3
危险类别码:R25
危险品运输编码:UN 2811 6.1/PG 2
海关编码:2934999090
危险品标志:T

生产方法及用途

合成路线

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图谱

Predict 1H proton NMR


13C NMR : Predict


1H NMR : Predict


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