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化合物简介

Treprostinil (marketed under the trade names Remodulin for infusion and Tyvaso for inhalation) is a vasodilator that is used for the treatment of pulmonary arterial hypertension. Treprostinil is a synthetic analog of prostacyclin (PGI2).

基本信息

CAS:81846-19-7
中文别名:曲前列环素;曲前列尼尔;
英文别名:Uniprost;LRX-15;[14C]-Treprostinil;UNII-RUM6K67ESG;Treprostinil;treprostinol;2-((1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-((S)-3-hydroxyoctyl)-1H-cyclopenta[b]naphthalen-5-yloxy)acetic acid;2-[[(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[g]naphthalen-5-yl]oxy]acetic acid;Tyvaso;15AU81;Remodulin;
分子式:C23H33NaO5
分子量:412.495
精确质量:412.223
Psa:89.82
Logp:2.2485

编号系统

UNII:RUM6K67ESG

物化性质

密度:1.158g/cm3
沸点:587.1ºC at 760mmHg
闪点:199.3ºC
折射率:1.553

安全信息

生产方法及用途

合成路线

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


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