Rifaximin (trade names:RCIFAX, Rifagut, Xifaxan, Zaxine) is a semisynthetic antibiotic based on rifamycin. It has poor oral bioavailability, meaning that very little of the drug will be absorbed into the blood stream when it is taken orally. Rifaximin is used in the treatment of traveler's diarrhea, irritable bowel syndrome, and hepatic encephalopathy, for which it received orphan drug status from the U.S. Food and Drug Administration in 1998.

CAS：80621-81-4
中文别名：利福昔明;地龙提取物;4-脱氧-4\'-甲基吡啶并[1\',2\'-1,2]咪唑并[5,4-C]利福素SV;
英文别名：fatroximin;l105;28e))-27r;Rifaximin;XIFAXAN;normix;RIFAMIXIN;RIFACOL;rifaxidin;l105sv;
分子式：C43H51N3O11
分子量：785.879
精确质量：785.352
Psa：198.38
Logp：6.2958

UNII：L36O5T016N

外观与性状：红色-橙色结晶粉末
密度：1.366 g/cm3
熔点：200-205ºC(dec)
折射率：1.633
储存条件：0-6ºC

RTECS号：KD1576000

用途
适用于革兰氏阳性菌及阴性菌，需氧及厌氧细菌所致急慢性肠道感染，腹泻综合症，肠道菌群改变所致腹泻等。