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化合物简介
An intermediate in the preparation of antitumor agents, antiinflammatory agents and tyrosine kinase inhibitors
基本信息
CAS：76360-82-2
中文别名：2-(甲硫基)-4-(甲氨基)嘧啶-5-甲酸乙酯;4-(甲基氨基)-2-(甲基磺酰基)-5-嘧啶羧酸乙酯;
英文别名：ethyl 4-(methylamino)-2-(methylthio)pyrimidine-5-carboxylate;4-Methylamino-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester;4-(Methylamino)-2-(methylthio)pyrimidine-5-carboxylic Acid Ethyl Ester;ethyl 4-methylamino-2-methylsulfanylpyrimidine-5-carboxylate;Ethyl4-(methylamino)-2-(methylsulfanyl)-5-pyrimidinecarboxylate;4-methylamino-2-methanesulfanyl-pyrimidine-5-carboxylic acid ethyl ester;
分子式：C9H13N3O2S
分子量：227.283
精确质量：227.073
Psa：89.41
Logp：1.4899
中文别名：2-(甲硫基)-4-(甲氨基)嘧啶-5-甲酸乙酯;4-(甲基氨基)-2-(甲基磺酰基)-5-嘧啶羧酸乙酯;
英文别名：ethyl 4-(methylamino)-2-(methylthio)pyrimidine-5-carboxylate;4-Methylamino-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester;4-(Methylamino)-2-(methylthio)pyrimidine-5-carboxylic Acid Ethyl Ester;ethyl 4-methylamino-2-methylsulfanylpyrimidine-5-carboxylate;Ethyl4-(methylamino)-2-(methylsulfanyl)-5-pyrimidinecarboxylate;4-methylamino-2-methanesulfanyl-pyrimidine-5-carboxylic acid ethyl ester;
分子式：C9H13N3O2S
分子量：227.283
精确质量：227.073
Psa：89.41
Logp：1.4899
编号系统
物化性质
密度：1.24 g/cm3
沸点：368.9ºC at 760 mmHg
闪点：176.9ºC
沸点：368.9ºC at 760 mmHg
闪点：176.9ºC
安全信息
海关编码：2933599090
生产方法及用途
合成路线
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参考文献
Goldstein, David M.; Soth, Michael; Gabriel, Tobias; Dewdney, Nolan; Kuglstatter, Andreas; Arzeno, Humberto; Chen, Jeffrey; Bingenheimer, William; Dalrymple, Stacie A.; Dunn, James; Farrell, Robert; Frauchiger, Sandra; La Fargue, Joann; Ghate, Manjiri; Graves, Bradford; Hill, Ronald J.; Li, Fujun; Litman, Renee; Loe, Brad; McIntosh, Joel; McWeeney, Daniel; Papp, Eva; Park, Jaehyeon; Reese, Harlan F.; Roberts, Richard T.; Rotstein, David; San Pablo, Bong; Sarma, Keshab; Stahl, Martin; Sung, Man-Ling; Suttman, Rebecca T.; Sjogren, Eric B.; Tan, Yunchou; Trejo, Alejandra; Welch, Mary; Weller, Paul; Wong, Brian R.; Zecic, Hasim Journal of Medicinal Chemistry, 2011 , vol. 54, # 7 p. 2255 - 2265
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
