Isradipine (tradenames DynaCirc, Prescal) is a calcium channel blocker of the dihydropyridine class. It is usually prescribed for the treatment of high blood pressure in order to reduce the risk of stroke and heart attack. More recent research in animal models suggests that isradipine may have potential uses for treating Parkinson's disease Chan et al. 2007.

CAS：75695-93-1
中文别名：地拉平;4-(2,1,3-苯并二唑-4-基)-1,4-二氢-2,6-二甲基-3,5-吡啶二羧酸异丙基甲酯;4-(4-苯并呋咱基)-2,6-二甲基-1,4-二氢-3,5-吡啶二羧酸甲酯1-甲基乙酯;4-(4-苯并呋喃基)-1,4-二氢-2,6-二甲基-3,5-吡啶二羧酸异丙基甲酯;伊拉地平;
英文别名：DynaCirc;Esradin;Iomir;4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydro-3-isopropyloxycarbonyl-pyridine-5-carboxylic acid methyl ester;Prescal;Clivoten;Lomir;Rebfiden;4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-3-methoxycarbonyl-pyridine-5-carboxylic acid isopropyl ester;Isradipin;Presca;Dynacrine;
分子式：C19H21N3O5
分子量：371.387
精确质量：371.148
Psa：103.55
Logp：2.911

MDL号：MFCD00153820

外观与性状：黄色固体
密度：1.249 g/cm3
沸点：501.9ºC at 760 mmHg
熔点：166-1680C
闪点：257.4ºC
储存条件：2-8ºC

安全说明：S22-S24/25
WGK Germany：3

生产方法
苯并呋咱-4-甲醛和3-氨基丁烯酸甲酯及乙酰乙酸异丙酯缩合，即得伊拉地平。 新型钙拮抗剂，兼有降压、抗心绞痛和抗动脉硬化作用。用于治疗原发性高血压、心绞痛和动脉硬化症等。
用途
新型钙拮抗剂，兼有降压、抗心绞痛和抗动脉硬化作用。用于治疗原发性高血压、心绞痛和动脉硬化症等。