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  • 8,8-dimethyl-3-(2,4,5-trimethoxyphenyl)pyrano[2,3-f]chromen-4-one

化合物简介

Barbigerone is one of a few pyranoisoflavones among several groups of isoflavones. It was first isolated from the seed of a leguminous plant Tephrosia barbigera; hence the name \"barbigerone\". Members of the genus Millettia are now known to be rich in barbigerone, including M. dielsiena, M. ferruginea, M. usaramensis, and M. pachycarpa. It has also been isolated from the medicinal plant Sarcolobus globosus. Barbigerone from S. globosus is validated to have significant antioxidant property. Barbigerone exhibits profound antiplasmodial activity against the malarial parasite Plasmodium falciparum. It is also demonstrated that it has anti-cancer potential as it causes apoptosis of murine lung-cancer cells.

基本信息

CAS:75425-27-3
中文别名
英文别名:barbigerone;B-allenyl-9-BBN;
分子式:C23H22O6
分子量:394.417
精确质量:394.142
Psa:67.13
Logp:4.67

编号系统

物化性质

密度:1.229g/cm3
沸点:574.4ºC at 760 mmHg
闪点:250.5ºC
折射率:1.581

安全信息

生产方法及用途

合成路线

上游原料

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图谱

1H NMR : Predict


13C NMR : Predict


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