Perafensine (INN) (code name HR-459) is a drug which was investigated as an antidepressant but was never marketed. It has been reported to antagonize the effects of reserpine and to inhibit the reuptake of norepinephrine (norepinephrine reuptake inhibitor); whether it also affects the reuptake of serotonin or dopamine is unclear.

CAS：72444-62-3
中文别名：
英文别名：1-Phenyl-3-(1-piperazinyl)isoquinoline;1-phenyl-3-piperazin-1-yl-isoquinoline;1-Phenyl-3-piperazinoisoquinoline;3-piperazino-1-phenyl-isoquinoline;Perafensine [INN];UNII-WU6989IN6X;Perafensine;
分子式：C19H19N3
分子量：289.374
精确质量：289.158
Psa：28.16
Logp：3.7052

UNII：WU6989IN6X

密度：1.155g/cm3
沸点：503.6ºC at 760 mmHg
闪点：258.4ºC
折射率：1.641