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化合物简介
Nortriptyline is a second-generation tricyclic antidepressant (TCA) marketed as the hydrochloride salt under the trade names Sensoval, Aventyl, Pamelor, Norpress, Allegron, Noritren and Nortrilen. It is used in the treatment of major depression and childhood nocturnal enuresis (bedwetting). Its off-label uses include treatment of chronic fatigue syndrome, chronic pain and migraine, and labile affect in some neurological disorders.
基本信息
CAS:72-69-5
中文别名:
英文别名:allegron;Aventyl;Sesaval;notriptyline;Avantyl;desmethylamitriptyline;[14C]-Nortriptyline;NORTRIPTYLINE;Psychostyl;Ateben;noramitriptyline;lambeck;Noritren;Lumbeck;
分子式:C19H21N
分子量:263.377
精确质量:263.167
Psa:12.03
Logp:4.2173
中文别名:
英文别名:allegron;Aventyl;Sesaval;notriptyline;Avantyl;desmethylamitriptyline;[14C]-Nortriptyline;NORTRIPTYLINE;Psychostyl;Ateben;noramitriptyline;lambeck;Noritren;Lumbeck;
分子式:C19H21N
分子量:263.377
精确质量:263.167
Psa:12.03
Logp:4.2173
编号系统
UNII:BL03SY4LXB
物化性质
密度:1.084 g/cm3
沸点:403.4ºC at 760 mmHg
闪点:194.9ºC
折射率:1.633
沸点:403.4ºC at 760 mmHg
闪点:194.9ºC
折射率:1.633
安全信息
海关编码:2921499090
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict

1H NMR : Predict

Mass spectrum (electron ionization)
