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化合物简介
Triclabendazole (commercial names: veterinary, liquid: Fasinex; human, tablets: Egaten, both manufactured by Novartis) is a member of the benzimidazole family of anthelmintics. The benzimidazole drugs share a common molecular structure, triclabendazole being the exception in having a chlorinated benzene ring but no carbamate group. Benzimidazoles such as triclabendazole are generally accepted to bind to beta-tubulin and prevent the polymerization of the microtubules of which they are part.
基本信息
CAS:68786-66-3
中文别名:三氯苯咪唑;5-氯-6-(2,3-二氯苯氧基)-2-甲硫基-1H-苯并咪唑;三氯苯达唑;5-氯-6-(2,3-二氯苯氧基)-2-(甲硫基)-1H-苯并咪唑;
英文别名:6-Chloro-5-(2,3-dichlorophenoxy)-2-methylthio-benzimidazole;
分子式:C14H9Cl3N2OS
分子量:359.658
精确质量:357.95
Psa:63.21
Logp:6.0373
中文别名:三氯苯咪唑;5-氯-6-(2,3-二氯苯氧基)-2-甲硫基-1H-苯并咪唑;三氯苯达唑;5-氯-6-(2,3-二氯苯氧基)-2-(甲硫基)-1H-苯并咪唑;
英文别名:6-Chloro-5-(2,3-dichlorophenoxy)-2-methylthio-benzimidazole;
分子式:C14H9Cl3N2OS
分子量:359.658
精确质量:357.95
Psa:63.21
Logp:6.0373
编号系统
MDL号:MFCD03147039
物化性质
外观与性状:白色至棕色结晶粉末
密度:1.59 g/cm3
沸点:495.9ºCat 760 mmHg
熔点:175-176°C
闪点:253.7ºC
折射率:1.724
稳定性:Stability
储存条件:库房低温,通风,干燥
密度:1.59 g/cm3
沸点:495.9ºCat 760 mmHg
熔点:175-176°C
闪点:253.7ºC
折射率:1.724
稳定性:Stability
储存条件:库房低温,通风,干燥
安全信息
安全说明:S26; S36
危险类别码:R36/37/38
WGK Germany:3
海关编码:2933990090
危险品标志:Xn
危险类别码:R36/37/38
WGK Germany:3
海关编码:2933990090
危险品标志:Xn
生产方法及用途
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图谱
Predict 1H proton NMR

13C NMR : Predict

1H NMR : Predict
