化学科研者一站式服务平台
化合物简介
Afimoxifene, also known as 4-hydroxytamoxifen (4-OHT, 4-HT, OHTAM, others), is a selective estrogen receptor modulator which is the active metabolite of tamoxifen. Afimoxifene is a transdermal gel formulation and is being developed by Ascend Therapeutics, Inc. under the trademark TamoGel.
基本信息
CAS：68392-35-8
中文别名：阿非昔芬;
英文别名：Propiophenone,4\'-[2-(diethylamino)ethoxy]-,hydrochloride;1-[4-(2-Diaethylamino-aethoxy)-phenyl]-propan-1-on,Hydrochlorid;1-[4-(2-diethylaminoethyloxy)phenyl]propan-1-one hydrochloride;4-hydroxytamoxifene;1-[4-(2-dimethylaminoethoxy)phenyl]-1-(4-hydroxyphenyl)-2-phenylbut-1-ene;(E,Z)-4-hydroxytamoxifen;1-[4-(2-diethylamino-ethoxy)-phenyl]-propan-1-one,hydrochloride;
分子式：C26H29NO2
分子量：387.514
精确质量：387.22
Psa：32.7
Logp：5.7017
中文别名：阿非昔芬;
英文别名：Propiophenone,4\'-[2-(diethylamino)ethoxy]-,hydrochloride;1-[4-(2-Diaethylamino-aethoxy)-phenyl]-propan-1-on,Hydrochlorid;1-[4-(2-diethylaminoethyloxy)phenyl]propan-1-one hydrochloride;4-hydroxytamoxifene;1-[4-(2-dimethylaminoethoxy)phenyl]-1-(4-hydroxyphenyl)-2-phenylbut-1-ene;(E,Z)-4-hydroxytamoxifen;1-[4-(2-diethylamino-ethoxy)-phenyl]-propan-1-one,hydrochloride;
分子式：C26H29NO2
分子量：387.514
精确质量：387.22
Psa：32.7
Logp：5.7017
编号系统
UNII：17197F0KYM
物化性质
密度：1.092
安全信息
危险标志：GHS07, GHS08
危险性描述：H302; H312; H332; H361
信号词：Warning
危险性防范说明：P280
危险性描述：H302; H312; H332; H361
信号词：Warning
危险性防范说明：P280
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
