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  • (2S)-2-[(3R,5S)-3,5-dihydroxy-1-adamantyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]acetic acid

化合物简介

Boc-3,5-dihydroxy-1-adamantyl-L-glycine is a reactant in the synthesis of of Saxagliptin, a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.

基本信息

CAS:681282-72-4
中文别名
英文别名:TRI048;
分子式:C17H27NO6
分子量:341.399
精确质量:341.184
Psa:119.58
Logp:1.6149

编号系统

物化性质

安全信息

生产方法及用途

合成路线

上游原料

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图谱

1H NMR : Predict


13C NMR : Predict


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