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化合物简介

Terconazole is an antifungal drug used to treat vaginal yeast infection. It comes as a lotion or a suppository and disrupts the biosynthesis of fats in a yeast cell. It has a relatively broad spectrum compared to azole compounds but not triazole compounds. Testing shows that it is a suitable compound for prophylaxis for those that suffer from chronic vulvovaginal candidiasis.

基本信息

CAS:67915-31-5
中文别名:1-[4-[[(2R,4S)-2-(2,4-二氯苯基)-2-(1,2,4-三唑-1-基甲基)-1,3-二氧戊环-4-基]甲氧基]苯基]-4-丙-2-基哌嗪;曲康唑;
英文别名:Terconagole;Triaconazole;Fungistat;
分子式:C26H31Cl2N5O3
分子量:532.462
精确质量:531.18
Psa:64.88
Logp:4.4656

编号系统

UNII:0KJ2VE664U

物化性质

密度:1.35g/cm3
沸点:681.8ºC at 760mmHg
熔点:126.3ºC
闪点:366.2ºC
折射率:1.64
储存条件:Store in original container in a cool dark place.

安全信息

危险标志:GHS07
危险性描述:H315; H319; H335; H413
信号词:Warning
危险性防范说明:P261; P305 + P351 + P338

生产方法及用途

用途
一种亲脂性三氮唑类广谱抗真菌药,其作用机制是高选择性地抑制真菌细胞的细胞色素酶。

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